In present times we are witnessing tremendous growth in technological advancement and its direct and positive impact on the innovations in the medicine and healthcare sectors. This has caused a direct influence on the life span of global populations, more so in the developed geographical regions. And, indisputably, with longevity, healthy aging has come to a sharp focus for maintaining the quality of life and lead a life full of zest, and to say the least, without any disabilities and dependencies.
Healthy aging in its ideal definition should be inclusive of healthy body systems as well as psychological wellbeing, we all know and have experienced too often that the latter is heavily dependent on the former. To put it simply, it takes enormous efforts to be psychologically fit in presence of any physical ailment. Another constant fear which grips the subconscious of in the aging individual is that of physical disability, especially the degenerative changes in the joints, especially the weight-bearing joints such as knee joints, gradually progressing from initial occasional mild joint ache to gradually increasing painful and limited joint movement. The symptoms almost certainly move closer to the onset of osteoarthritis, and a moderate to severe joint failure glares blatantly at the aging person, making them feel so helpless! Needless to mention, osteoarthritis is the highly prevalent and leading cause of disability in the aging population.
Medicinal herbs and spices from the Indian subcontinent have been used for ages with multiple clinical benefits and are being more and more backed up through research as potential therapeutic agents. Turmeric, through the phytoactive from its rhizome – curcuminoids, has been one such natural ingredient that has emerged out to be a pleiotropic ingredient with multiple pharmacological actions and myriad beneficial effects in a clinical setting.
Anti-inflammatory and antioxidant are among the broad spectrum of biological activities of curcuminoids. Research shows that curcuminoids exert anti-apoptotic effects on interleukin (IL)-1β- stimulated human articular chondrocytes; inhibit pro-inflammatory mediators including prostaglandin E2, nitric oxide, IL-6, and IL-8; and inhibit the production of matrix metalloproteinases. Despite these proven benefits of curcuminoids, their inherent poor bioavailability is a limiting factor that prevents the full-blown benefits of turmeric from reaching its user.
When administered orally, only a small amount of curcuminoids is absorbed, thus requiring multiple daily doses for gaining optimal effects. Such a high dosage is associated with poor compliance, particularly when used long-term.TurmXtra 60N is a novel turmeric formulation/product designed to overcome these hurdles and optimize the health benefits of turmeric and curcuminoids. TurmXtra 60N, in a single dose of 250 milligrams is not only shown to have similar absorption and bioavailability to multiple doses of standardized 95% turmeric extract but in the same small single daily dose, has also shown positive results in individuals suffering from chronic joint pain. The benefit of TurmXtra 60N is evident in maintaining healthy joints and has a major positive impact on healthy aging.